Selective Glucocorticoid Receptor Modulators (SGRMs) delay castrate-resistant prostate cancer growth.
Selective glucocorticoid receptor antagonist CORT125281 activates brown adipose tissue and alters lipid distribution in male mice.
A novel combined glucocorticoid-mineralocorticoid receptor selective modulator markedly prevents weight gain and fat mass expansion in mice fed a high-fat diet.
Identification of a selective glucocorticoid receptor modulator that prevents both diet-induced obesity and inflammation.
Glucocorticoid antagonism limits adiposity rebound and glucose intolerance in young male rats following the cessation of daily exercise and caloric restriction.
Effects of selective and non-selective glucocorticoid receptor II antagonists on rapid-onset diabetes in young rats.
Discovery of a novel non-steroidal GR antagonist with in vivo efficacy in the olanzapine-induced weight gain model in the rat.
Selective glucocorticoid receptor (type II) antagonists prevent weight gain caused by olanzapine in rats.
