The Design of MOMENTUM: A Prospective Study of the Prevalence of Endogenous Hypercortisolism in Individuals With Resistant Hypertension

Summary

Previously, the prospective CATALYST study (N=1,057) found endogenous hypercortisolism in 24% of individuals with difficult-to-control type 2 diabetes and in 40% of the subgroup who also had systolic blood pressure ≥135 mmHg despite taking ≥3 blood pressure-lowering medications
These findings demonstrated a need to investigate the prevalence of endogenous hypercortisolism in a wider population with resistant hypertension
The currently enrolling MOMENTUM study is designed to provide an estimate of endogenous hypercortisolism prevalence and its associated clinical characteristics in a US population of individuals with resistant hypertension
It is anticipated that the data from MOMENTUM will expand our understanding of the association between endogenous hypercortisolism and resistant hypertension