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1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as potent GR antagonists with reduced hERG inhibition and an improved pharmacokinetic profile.

September 18, 2018

Hunt et al. • 2015 • Bioorg Med Chem Lett. 2015;25(24):5720-5.

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https://corcept.com/wp-content/uploads/COR-logo.svg 0 0 jeremiah@devisedesigns.com https://corcept.com/wp-content/uploads/COR-logo.svg jeremiah@devisedesigns.com2018-09-18 00:00:002018-09-18 00:00:001H-Pyrazolo[3,4-g]hexahydro-isoquinolines as potent GR antagonists with reduced hERG inhibition and an improved pharmacokinetic profile.

Comparison of direct action of thiazolidinediones and glucocorticoids on renal podocytes: protection from injury and molecular effects.

September 18, 2018

Agrawal et al. • 2011 • Mol Pharmacol. 2011;80(3):389-99.

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https://corcept.com/wp-content/uploads/COR-logo.svg 0 0 jeremiah@devisedesigns.com https://corcept.com/wp-content/uploads/COR-logo.svg jeremiah@devisedesigns.com2018-09-18 00:00:002018-09-18 00:00:00Comparison of direct action of thiazolidinediones and glucocorticoids on renal podocytes: protection from injury and molecular effects.

Administration of a selective glucocorticoid antagonist attenuates electroconvulsive shock-induced retrograde amnesia.

September 18, 2018

Andrade et al. • 2012 • J Neural Transm (Vienna). 2012;119(3):337-44.

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https://corcept.com/wp-content/uploads/COR-logo.svg 0 0 jeremiah@devisedesigns.com https://corcept.com/wp-content/uploads/COR-logo.svg jeremiah@devisedesigns.com2018-09-18 00:00:002018-09-18 00:00:00Administration of a selective glucocorticoid antagonist attenuates electroconvulsive shock-induced retrograde amnesia.

Selection and early clinical evaluation of the brain-penetrant 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor UE2343 (Xanamem™).

November 15, 2017

Webster et al. • 2017 • Br J Pharmacol. 2017;174(5):396-408.

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https://corcept.com/wp-content/uploads/COR-logo.svg 0 0 jeremiah@devisedesigns.com https://corcept.com/wp-content/uploads/COR-logo.svg jeremiah@devisedesigns.com2017-11-15 00:00:002024-03-14 21:45:03Selection and early clinical evaluation of the brain-penetrant 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor UE2343 (Xanamem™).

High glucocorticoid receptor expression predicts short progression-free survival in ovarian cancer

November 15, 2017

Veneris et al • 2017 • Gynecol Oncol.

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https://corcept.com/wp-content/uploads/COR-logo.svg 0 0 jeremiah@devisedesigns.com https://corcept.com/wp-content/uploads/COR-logo.svg jeremiah@devisedesigns.com2017-11-15 00:00:002024-03-15 21:52:54High glucocorticoid receptor expression predicts short progression-free survival in ovarian cancer

Evaluation of evidence of adrenal insufficiency in trials of normocortisolemic patients treated with mifepristone.

October 15, 2017

Yuen et al. • 2017 • J Endocr Soc. 2017;1(4):237-246.

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https://corcept.com/wp-content/uploads/COR-logo.svg 0 0 jeremiah@devisedesigns.com https://corcept.com/wp-content/uploads/COR-logo.svg jeremiah@devisedesigns.com2017-10-15 00:00:002024-03-15 21:55:43Evaluation of evidence of adrenal insufficiency in trials of normocortisolemic patients treated with mifepristone.

The role of glucocorticoid receptors in metabolic syndrome and psychiatric illness.

September 21, 2017

Moraitis et al. • 2017 • J Steroid Biochem Mol Biol. 2017 Jan;165(Pt A):114-120.

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https://corcept.com/wp-content/uploads/COR-logo.svg 0 0 jeremiah@devisedesigns.com https://corcept.com/wp-content/uploads/COR-logo.svg jeremiah@devisedesigns.com2017-09-21 00:00:002024-03-15 21:57:07The role of glucocorticoid receptors in metabolic syndrome and psychiatric illness.

U500 Insulin Screening of Diabetic Patients Uncovers a Large Amount of Undiagnosed Hypercortisolism Consistent With Cushing’s Syndrome

January 15, 2017

Editorial Team • 2017 • Diabetes

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Mifepristone improves octreotide efficacy in resistant ectopic Cushing’s syndrome.

November 15, 2016

Moraitis AG, Auchus RJ. • 2016 • Case Rep Endocrinol. 2016;2016:8453801.

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New selective glucocorticoid receptor modulators reverse amyloid-β peptide-induced hippocampus toxicity.

November 15, 2016

Pineau et al. • 2016 • Neurobiol Aging. 2016;45:109-122.

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