Characterization of Patients With Difficult-to-Control Type 2 Diabetes and a Post–Dexamethasone Suppression Test Cortisol of 1.2–1.8 μg/dL: Findings From a Large Prospective Study

Summary  

  • Data collected in CATALYST allowed us to explore characteristics associated with different post-DST cortisol values and to better understand the impact of different post-DST cortisol levels on comorbidities
  • The results of this analysis suggest that there is a continuum of cardiometabolic risk as a function of nonsuppressible cortisol
  • As this analysis showed, individuals with post-DST cortisol 1.2–1.8 μg/dL share similarities in clinical characteristics with those who have DST results above the current hypercortisolism diagnostic cutoff, suggesting that further investigation of this group may be warranted


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