Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator.
Zalachoras et al. • 2013 • Proc Natl Acad Sci U S A. 2013;110(19):7910-7915.
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Antiglucocorticoid therapy for older adults with anxiety and co-occurring cognitive dysfunction: results from a pilot study with mifepristone.
Lenze et al. • 2014 • Int J Geriatr Psychiatry. 2014;29(9):962-9.
Rapid reversal of acute psychosis in the Cushing syndrome with the cortisol-receptor antagonist mifepristone (RU 486).
van der Lely et al. • 1991 • Ann Intern Med. 1991;114(2):143-4.
1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as potent GR antagonists with reduced hERG inhibition and an improved pharmacokinetic profile.
Hunt et al. • 2015 • Bioorg Med Chem Lett. 2015;25(24):5720-5.
Comparison of direct action of thiazolidinediones and glucocorticoids on renal podocytes: protection from injury and molecular effects.
Agrawal et al. • 2011 • Mol Pharmacol. 2011;80(3):389-99.
Administration of a selective glucocorticoid antagonist attenuates electroconvulsive shock-induced retrograde amnesia.
Andrade et al. • 2012 • J Neural Transm (Vienna). 2012;119(3):337-44.
Selection and early clinical evaluation of the brain-penetrant 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor UE2343 (Xanamem™).
Webster et al. • 2017 • Br J Pharmacol. 2017;174(5):396-408.
High glucocorticoid receptor expression predicts short progression-free survival in ovarian cancer
Veneris et al • 2017 • Gynecol Oncol.
Evaluation of evidence of adrenal insufficiency in trials of normocortisolemic patients treated with mifepristone.
Yuen et al. • 2017 • J Endocr Soc. 2017;1(4):237-246.
The role of glucocorticoid receptors in metabolic syndrome and psychiatric illness.
Moraitis et al. • 2017 • J Steroid Biochem Mol Biol. 2017 Jan;165(Pt A):114-120.